6 Best Rat & Mouse Poison

In this article, we have highlighted some of the best rat and mouse poison (aka Rodenticide baits poison) to use against the rodents your are facing.

Baits poisons (Rodenticides) are not designed for instant kill. The idea is for the rodent to mistake them as food, consume it and hopefully bring these poison back to the nest to share with the rest (it works “behind the scenes”). Hence when bait poison works, it is possible to drastically reduce the infestation.

Bait poison should be used in conjunction with rat traps to help get rid of rat and mouse problems most effectively.

Note: Bait poison should be used in uninhabited buildings (such as garages and barns) with no pets around. A safety bait station box should be used if need to use indoor, and use block type of mouse poison bait (instead of pellets).

Tip: It’s good to change bait brands and flavors to keep them interested

>> Related article: Best Natural Rat Bait Lures

Pros of using Rat & Mouse Poison
  • No bait shyness (as the killing takes time)
  • Potential for viral killing effect
  • Easy to use
  • Effective
  • Works behind-the-scene
Cons of using Rat & Mouse Poison
  • No instant kill
  • Rodent might not always fall for it
  • Might die in inaccessible locations causing odor problem
  • Can kill other small animals as well

1) Old Cobblers Farnam Just-One-Bite Bait Bar

The Just-One-Bite ll Bait Bar is designed for both indoor and outdoor to kill Norway rats, roof rats and house mice.

It uses bromadiolone as the active ingredient and one feeding can result in first dead rodents after 4-5 days after feeding begins.

Each purchase comes with 2 bars, and each bar can be easily broken into 8 pieces of 2 oz size bait. It features a hole in the middle for easy mounting in bait station.

Recommended Dosage:

  • For rats – 2 to 8 pieces per placement (15 to 30 ft apart)
  • For mice – 1 piece per placement (8 to 12 ft apart)
  • Tasty to vermin
  • Works on both rats and mice
  • Used indoor or outdoor
  • Can be mounted on bait station
  • Have option to use as one big piece or broken down
  • Need to break it to use as small pieces

Note: Avoid surfaces that come in contact with food and places where there’s a possibility of contaminating foods.

Note: Dispose dead rats immediately so other animals (i.e. birds) do not get secondary poisoning.

>> Pellet version here: Just-One-Bite Pellet Packs 

2) D-Con Rat & Mouse Bait Pellets

The D-Con Rat & Mouse Bait Pellets contains Brodifacoum that kills even warfarin resistant mice & rats in a single feeding.

It comes with 1 ready-to-use bait poison filled tray where users simply peel open & place in areas where rodents seem to frequent.

  • Tray option available
  • Convenient & easy to use (simply peel & place)
  • Kills even warfarin resistant mice & rats
  • Quite expensive

>> Available in these sizes: 1 Tray, 4 Bait, 4 Tray

3) JT Eaton 709-PN Bait Block Rodenticide Anticoagulant (Peanut Butter Flavor)

The JT Eaton Bait Block rodenticide is a anticoagulant bait with specially formulated blocks that have a peanut butter flavor to attract and eliminate mice and rats.

Similar to other bait poison, it uses active ingredient Diphacinone to eliminate rodents and pests a few days after feeding.

Every purchase comes with in a tamper evident resealable pail which contains 144 packs of 1-ounce rodenticide blocks. JT Eaton also offers a 1-year limited warranty which protect buyers against defects in material and workmanship.

  • Works on both rats and mice
  • Peanut butter flavoured
  • 1-year limited warranty
  • Resealable pail

Sidenote: JT Eaton is family owned and has operated since 1932

>> Available in these sizes: 1 Pail, 2 Pails, 3 Pails, 4 Pails & 5 Pails

4) Contrac Blox Rodent Control Rodenticide


The Contrac All-weather Blox Rodenticide is a multi-edged, single feeding rat and mouse poison bait formulated with a blend of food grade ingredients and low wax to yield a palatable and weatherable bait that attracts rodents.

It can be stored for at least 2-3 years when unopened and kept away from extreme temperatures. Once opened, it should last a year in normal conditions.

Every purchase comes in a 18 lb pail which contains about 288 blox (good value for the large pail size).

Sidenote: Possibility of secondary poisoning is very minimal with Contrac but if need to, vitamin K1 can act as an antidote to the poison.

  • Comes in green color
  • Value for money
  • Uses food grade ingredients
  • Long lasting
  • Can be stored away
  • Can be too much quantity for home use
Tip: Change out bait every 40 – 60 days if not eaten.

Tip 2: Blox comes in green color, hence when used outside, allows you to follow the turd trail to locate entry points.

Note: Very cold or warm temperatures will mold or sour the bait faster.

5) NEOGEN RODENTICIDE Ramik Rat & Mouse Bait Poison

The NEOGEN Rodenticide is an all weather bait poison that can be used both indoors and outdoors. It combines food processing technology and patented procedures to create a palatable and attractive rodenticide.

It’s fish flavored and high protein appeal attracts rodents even in difficult weather conditions.

Every pack contains 45 pieces of 43 gm mini bait packs.

  • Indoor & outdoors
  • Fish flavored & high protein appeal
  • Tiny pellet size (ideal for killing small mice)
  • Not effective on bigger rats
Note: Keep the pet’s water bowl indoor as rats might try to drink from there and end up passing the poison.

6) Tomcat Mouse Killer Poison

>> Best Indoor Mouse Bait Poison

The Tomcat Mouse Killer poison bait is designed for indoor use only.

It comes with tamper resistant disposable station that gives mice easy access to bait while keeping fingers and pet paws out.

Each bait poison block is lab tested to effectively kill up to 6 mice.

  • Comes with bait station
  • Ideal for indoor use
  • Lab tested

>> Related article: Best Rat & Mouse Traps

Safety Gloves

AMMEX Disposable Black Gloves (Box of 100)

Available in these sizes: S, M, L & XL


Rats are known to spoil (or destroy) anything that they come across and can cause sleepless nights as they run up and down during the night. And because they can manifest very quickly, actions must be taken to get rid of a rat the moment you spot one at home (see article: Rat vs Mouse).

Like the rat traps, there’s always a possibility that the rats will not fall for it. With the delayed killing effect of a bait poison, by the time the rats figured out that it’s poison, it might already be too late for them.

ALWAYS remember that no rodenticide poison is pet-safe. They CAN and WILL kill pets and other small animals if they consume it. Invest in a tamper-proof bait station if you need to use the rodenticide at home.

What do you think about using these poison rodenticides at a solution against rats & mice? Have you tried or are you thinking about trying? Let us know in the comment!

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