6 Best Rat & Mouse Poison

In this article, we have highlighted some of the best rat and mouse poison (aka Rodenticide baits poison) to use against the rodents your are facing.

Baits poisons (Rodenticides) are not designed for instant kill. The idea is for the rodent to mistake them as food, consume it and hopefully bring these poison back to the nest to share with the rest (it works “behind the scenes”). Hence when bait poison works, it is possible to drastically reduce the infestation.

Bait poison should be used in conjunction with rat traps to help get rid of rat and mouse problems most effectively.

Note: Bait poison should be used in uninhabited buildings (such as garages and barns) with no pets around. A safety bait station box should be used if need to use indoor, and use block type of mouse poison bait (instead of pellets).

Tip: It’s good to change bait brands and flavors to keep them interested

>> Related article: Best Natural Rat Bait Lures

1D-Con Rodent Bait Pellets Check Price
2JT Eaton Bait Block Rodenticide Check Price
3Tomcat Rat Liquid Bait by MOTOMCO Check Price
4Contrac Blox Rat & Mice Control Rodenticider Check Price
5NEOGEN RODENTICIDE Ramik Green Bait Poison Check Price
6Tomcat Rodent Killer Poison Check Price

Pros of using Rat & Mouse Poison
  • No bait shyness (as the killing takes time)
  • Potential for viral killing effect
  • Easy to use
  • Effective
  • Works behind-the-scene
Cons of using Rat & Mouse Poison
  • No instant kill
  • Rodent might not always fall for it
  • Might die in inaccessible locations causing odor problem
  • Can kill other small animals as well

1) D-Con Rat & Mouse Bait Pellets

The D-Con Rat & Mouse Bait Pellets contains Brodifacoum that kills even warfarin resistant rodents in a single feeding.

It comes with 1 ready-to-use bait poison filled tray where users simply peel open & place in areas where rodents seem to frequent.

  • Easy to set up & use 
  • Kills even warfarin resistant rodents
  • Quite expensive

2) JT Eaton Bait Block Rodenticide Anticoagulant (Peanut Butter Flavored)

The Bait Block Rodenticide by JT Eaton is a specially formulated anticoagulant bait block that eliminates mice and rats by attracting them using it’s peanut butter flavored formula.

Similar to other bait poison, it uses active ingredient Diphacinone to eliminate rats and other pests within a few days after feeding.

Every purchase comes with a tamper evident resealable pail which contains 144 packets of 1-ounce rodenticide blocks. JT Eaton also offers a 1-year limited warranty which protect buyers against defects in material and workmanship.

  • Works on both rats and mice
  • Peanut butter flavoured
  • 1-year limited warranty
  • Resealable pail

Sidenote: JT Eaton is family owned and has operated since 1932

3) Tomcat Rat Liquid Bait Concentrate by MOTOMCO

The Tomcat Mouse & Rat liquid bait poison by MOTOMCO features Diphacinone as its active ingredient to get rid of rodents at mass.

Note: It is not recommended for use at home if you have pets or kids that will likely consume the bait.

This unique product works using the very fact that rodents at your house will and have to drink water regardless of how smart they’ve gotten to learn to avoid the rat traps and poison baits you set up. As such, it works exceptionally well in dry environment and conditions.

Tip: Put more concentrate into the mix to make it stronger for even better effectiveness, but not too much that rodents don’t fall for it. As with any bait like poison, be patient with the results.

Pro-tip: If you do have suspicious rats to deal with, try setting the water stations with non treated water to get the rats comfortable with the water source as they notice that no friends are dying. Once you’ve gained the trust, go ahead and replace water with the liquid concentrate.

  • Ideal for rodents that won’t take bait or fall for traps
  • Designed for mass killing
  • Great alternative to typical bait pellets
  • Potential to kill other animals

>> Buy Water Feeder here: Miller Feeder

4) Contrac Blox Rodenticide

This Rodenticide by Contrac All-weather Blox is a single feeding rodent poison bait formulated with a blend of ingredients which resulted in this deadly bait that is weather resistant, and can stay attractive to rodents to take the bait.

It can be stored for at least 2 to 3 years when unopened and kept away from extreme temperatures. Once opened, it can last for at least 1 year in normal conditions.

Every purchase comes in a 18 lb pail which contains about 288 blox (good value for the large pail size).

Sidenote: While the possibility of secondary poisoning is unlikely with this bait, but if need to, vitamin K1 can act as an antidote to the poison.

  • Comes in green color
  • Value for money
  • Uses food grade ingredients
  • Long lasting
  • Can be stored away
  • Can be too much quantity for home use
Tip: Change out bait every 40 – 60 days if not eaten.

Tip 2: Box comes in green color, hence when used outside, allows you to follow the turd trail to locate entry points.

Note: Very cold or warm temperatures will mold or sour the bait faster.

5) NEOGEN RODENTICIDE Ramik Green Rodent Bait Poison

The NEOGEN Rodenticide is an all weather bait poison that can be used both indoors and outdoors. It combines food processing technology and patented procedures to create a palatable and attractive rodenticide.

It’s fish flavored and high protein appeal attracts rodents even in difficult weather conditions.

Every pack contains 45 pieces of 43 gm mini bait packs.

  • Indoor & outdoors
  • Fish flavored & high protein appeal
  • Tiny pellet size (ideal for killing small mice)
  • Not effective on bigger rats
Note: Keep the pet’s water bowl indoor as rats might try to drink from there and end up passing the poison.

6) Tomcat Rodent Killer Bait Poison

>> Best Indoor Mouse Bait Poison

The Tomcat Mouse Killer bait poison is designed for indoor use only.

Each purchase includes a disposable rat bait station that is tamper resistant and allows easy access for mice to enter and feed on bait, while keeping fingers and pet paws out.

Each bait poison block is lab tested to effectively kill up to 6 mice.

  • Comes with bait station
  • Ideal for indoor use
  • Lab tested

>> Related article: Best Rat & Mouse Traps

Safety Gloves

AMMEX Disposable Black Gloves (Box of 100)

Available in these sizes: S, M, L & XL


Rats are known to spoil (or destroy) anything that they come across and can cause sleepless nights as they run up and down during the night. And because they can manifest very quickly, actions must be taken to get rid of a rat the moment you spot one at home (see article: Rat vs Mouse).

Like the rat traps, there’s always a possibility that the rats will not fall for it. With the delayed killing effect of a bait poison, by the time the rats figured out that it’s poison, it might already be too late for them.

ALWAYS remember that no rodenticide poison is pet-safe. They CAN and WILL kill pets and other small animals if they consume it. Invest in a tamper-proof bait station if you need to use the rodenticide at home.

What do you think about using these poison rodenticides at a solution against rats & mice? Have you tried or are you thinking about trying? Let us know in the comment!