8 Best Bed Bug Killer (2023 Edition)

This article features some of the best bed bug killers in the market that can aid you in battling the blood-sucking nasty night crawlers. It includes bed bug sprays, bed bug insecticides as well as bed bug powders for your selection.

While pests are just a pain to have, bed bugs are some of the worst to have… There’s nothing quite as horrifying as having these little suckers crawling on you when you’re asleep!

Bed bugs have become a common household problem in the United States due to their undercover behavior combined semi-fast reproduction ability (females can lay an egg or two every day which hatches after ten days).

There’s no single treatment that is 100% guaranteed to solve your bed bug issues, but integrating these bed bug killers can help reduce their population, and when combined with other controlling methods, can help get rid of your bed bug problems.

1Talstar Pro Bed Bug Killer Check Price
2Bed Bug Spray by EcoRaider (Extended Protection) Check Price
3Eco Defense Bed Bug Spray Check Price
4Temprid FX Pest Control Insecticide Check Price
5Demand CS Bed Bugs Professional Pest Control Killer Insecticide Check Price
6CimeXa Insecticide Dust Check Price
7Harris Diatomaceous Earth Check Price
8Climbup Insect Interceptor Bed Bug Trap Check Price

1) Talstar Pro Bed Bug Killer

The Talstar Pro is a powerful bed bug killer designed with the pros in mind. It uses 7.9% Bifenthrincan as the active Ingredient and be used both Inside the house and out around the perimeter.

On top of bed bugs, Talstar Pro also kills over 75 different pests including mosquitoes, cockroaches, fleas, spiders, ants, ticks, earwigs, millipedes and more.

It is pet safe when dry, but avoid letting dog and cat into treatment area for at least 48 hours.

  • Used by professionals
  • Also works great on roaches, spiders, ants and fleas.
  • Does not kill plants when used outdoor
  • Pump spray sold separately

2) EcoRaider Bed Bug Spray (with Extended Residual Protection)

Brand: EcoRaider

Also featured in our round-up for best bed bug spray, this BioBased bed bug killer spray by EcoRaider is a safe and USDA certified spray that can be used directly on box springs and mattresses (Eco Raider uses a non-staining formula that does not leave marks on the furniture or floor).

This all-natural spray is pet and child safe, and is research entomologist tested to effectively get rid of the tiny bed bugs in both commercial and private establishments. It is also recommended for use in sensitive environments (i.e. schools, clinics, health-care facilities and public areas).

It has a two-week residual effect after dry and it’s non-toxic and destroys any kind of bed bugs (including those resistant to insecticides), in both the larval and adult stage.

  • Non-toxic & eco-friendly
  • Long residual effect (kills for weeks)
  • Field tested by research entomologists
  • Eliminates even resistant bed bugs
  • Kills all stages of bed bugs
  • Pets and humans friendly
  • Smell can be too strong

Side note: Unlike chemical-based products, EcoRaider is uses active ingredients extracted from plants to attacks the neuron receptor only exists in invertebrates (i.e. insects), but do not affect vertebrates (i.e. humans, birds, animals and fish). This  immediate causes paralysis and death to the bed bugs.

Tip: Try to apply treatment at areas that are ventilated.

>> Related article: Best Bed Bug Spray

3) Eco Defense Bed Bug Spray

Brand: Eco Defense

The bed bug killer spray by Eco Defense is a non-toxic spray that features a unique blend of organic ingredients that kill bed bugs in all stages of their life (eggs and adults).

It contains no chemicals, pesticides, or poisonous Ingredients and can be applied directly to mattress cover and sheets without fear of staining.

Eco Defense also offers a 60-day trial period guarantee.

  • Non-toxic & organic ingredients
  • Non-staining formula
  • Kills all stages of bed bugs
  • Pet and child safe
  • Kills on contact
  • Money back guarantee
  • Smell can be strong

Tip: Consider adding Harris Diatomaceous Earth Bed Bug Powder to treatment area after drying completely.

4) Temprid FX Pest Control Insecticide

The Temprid FX is a long lasting bed bug insecticide designed for both indoor and outdoor application. It uses active ingredient (beta-cyfluthrin) that is powerful against pests, and has no odor and less visible residue.

Each bottle of Temprid FX can make an average of 30 gallons formula that treats up to 30,000 sq. ft. outdoors.

This suspension concentrate delivers the power of a powder formulation in a liquid. It is non-staining, easy to use and has a long lasting residual of up to 3 months.

  • Very concentrated (don’t have to use much)
  • Also works on ants, spiders, roaches & silverfish
  • No odor and non-staining
  • Long residual (up to 3 months)
  • Small measuring section on the bottle
  • Sprayer sold separately

Note: Insecticide should be shaken before use. Be sure to wear a face mask when using product. If applied on turf, don’t do it more than 6 timer per year as that can cause serious damage.

Tip: Don’t apply when it is raining or just after rain. Be sure to re-apply if it rains within 24 hours after applying.

5) Demand CS Bed Bugs Professional Pest Control Killer Insecticide

The Demand CS insecticide offers heavy duty indoor and outdoor control with little to no odor or staining. 

Demand’s micro-encapsulated technology leaves tens of thousands of micro particles that sticks to the surface of the treatment area, killing bed bugs when they come in contact. This results in fast bed bug knock-down as well as offers long-term protection (about 90 days after application).

This water-based insecticide concentrate is up to 200 times more active as compared to older pyrethroid materials (with declining results) is designed not only to work better, but also longer.

On top of bed bugs, Demand CS also works on more than 30 common pests including ants, wasps, spiders, flies, ticks and fleas.

  • Only a small amount needed
  • Long residue protection
  • No odor & non staining
  • Also kills other pests
  • Sprayer sold separately

6) CimeXa Insecticide Dust

The CimeXa bed bug dust is an odorless and non-staining insecticide powder designed to kill bed bugs on contact.

How it works: The fine particles of silicon will stick to passing bed bugs (electrostatic attraction). Once attached, the dust will damages the bug’s cuticle (the outer covering of the bug’s exoskeleton), causing rapid dehydration and eventually death.

CimeXa dust can kill bed bug adults (including pyrethroid-resistant bed bugs), nymphs and eggs. On top of bed bugs, it also kills other pests like fleas, ticks, lice, cockroaches, ants, firebrats, mites, silverfish, spiders and even drywood termites.

When undisturbed, it remains effective for up to 10 years.

  • Long lasting kill
  • Also works on other bugs
  • Don’t need to apply alot
  • Kills faster than DE (Diatomaceous Earth) dust
  • Puffer sold separately (but well worth it)

Tip: Be sure to apply sparingly for best results. Invest in puffer to help apply more evenly and reach tougher spots.

>> Related article: Best Bed Bug Powder

7) Harris Diatomaceous Earth

The Harris Diatomaceous Earth long lasting powder combines crystalline silica and amorphous silica as it’s active ingredient to kill bed bugs.

It is almost pure white as compared to darker colored Diatomaceous Earth which often contains impurities like iron and clay

It is non-toxic and safe for use both in the household and out in the garden. Listed with the Organic Materials Review Institute, it is also safe for humans, dogs & cats.

Where to Apply Diatomaceous Earth

Sprinkle a thin layer of dust directly where bed bug live and breed:

  • Kitchens and behind appliances, furniture and cracks in walls or furnitures.
  • Attics, Basements and Garages
  • Beds and Mattresses
  • Exterior of house areas along entryways and windows (kill before bed bugs enter the home).
  • Non-toxic & Organic
  • No smell
  • Easy to use
  • Safe to use around humans and pets
  • Powder can clog vacuum when cleaning (as with all powder solutions)
  • Not for immediate killing

Tip: Don’t bother buying the sprayer. Simply sprinkled it on treatment area.

Tip 2: Use in conjunction with a spray like Hot Shot for immediate effect.

>> Bonus

8) Climbup Interceptor Bed Bug Trap

The ClimbUp Bed Bug trap intercepter is a set-and-forget monitoring system to help provide early detection of bed bugs at home. On top of early detection of potential attack by bed bugs, it also helps identify whether a piece of furniture is still infested with bed bugs after a treatment.

It features a dual-well which allow users to determine which direction the bed bugs are crawling.

How it traps: Approaching bed bugs that attempts to climb up the leg of your furniture (i.e sofa, bed frame) will fall into the outer well of the trap. Escaping bed bugs trying to leave the furniture will get trapped and stuck in the center well.

Each purchase comes with 4 pesticide-free interceptors that can fit any furniture with posts (aka ‘legs’) of up to 370 in diameter. It is made with thick polypro material to resist cracking with age.

  • Can be used on any furnitures with legs
  • Helps monitor and detect problem
  • Pesticide-free
  • Easy to use
  • Made in USA
  • Gives a little more peace of mind at night
  • Can only be used on furnitures with legs
  • Not really a bed bug killer
  • Chances that trapped bug might climb back (see tip below)

Tip: Put some CimeXa Insecticide Dust to kill trapped bugs.

Note: Place something below to support when used on carpet to prevent breaking it.

[May: Monitoring devices such as ClimbUp are useful for confirming the presence of bed bugs when a visual inspection cannot. It also provides a barrier between the floor and the bed since that’s where they actually get to you – as bed bugs can’t jump or fly.]

>> Related Article: Best Bed Bug Traps


Getting bed bugs can be a traumatizing experience and if you’ve ever dealt with them, you know it’s something you get over quickly.

But not all hopes are lost, bed bug problem can be eliminated over time. It takes effort, consistency and depending on the infestation level, it can get pretty costly (i.e. treatment cost, cost of replacing household items).

You CAN beat these things. Be persistent and don’t give up!

Be aggressive and devote at least an entire weekend or more to it. For persistent infestations, consider consulting a professional applicator.